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Subject: Re: Chemical- and toxin-induced hepatotoxicity


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hepatitis c outreach project
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Date Posted: Fri, August 22 2003, 6:56:58 PDT
In reply to: Zimmerman HJ; Gastroenterol Clin North Am. 1995 Dec;24(4):1027-45 's message, "Chemical- and toxin-induced hepatotoxicity" on Fri, August 22 2003, 6:54:12 PDT

TOXIC DANGERS IN THE HOME

Vinyl: A Greenpeace report published in June of 2001 examined the hazardous effects of exposure to chemicals found in vinyl plastic childcare products and home furnishings. When Greenpeace analyzed vinyl mattress pads, vinyl flooring and other items, they found a range of additives such as phthalates, organotins, lead, cadmium and bisphenol A. These chemicals are known to be responsible for adverse heath effects such as liver cancer, kidney damage, and various nervous and respiratory problems. Some of the name brands that were tested include Gerber, Carter’s, Graco, Armstrong and Mannington.

Lead (airborne): Most candle wicks are made from cotton but those that need extra support require a metal core. Despite a warning issued by the U.S. Consumer Product Safety Commission (CSPC), candles with lead-core wicks (as opposed to zinc or tin wicks) are still being manufactured today. These candles release concentrations of lead into the air that range from nine to 33 times higher than the acceptable federal limit. Lead is particularly harmful to children and can cause damage to the central nervous system, reproductive system, and kidneys. Even low levels of lead can lead to decreased intelligence, impaired neurobehavioral development, decreased stature and growth, and impaired hearing acuity. In order to be sure that your candles are lead free, avoid candles with metal cores of any kind as it is difficult for the average consumer to determine if the metal wick is lead or some other non-harmful metal.

Lead Paint: A source of continuing danger to children under the age of six is the existence of lead paint in older (built before 1978), poorly maintained buildings, or in buildings that have undergone renovations. The problem is most prevalent in poorer neighborhoods where there is a greater likelihood that painting has not been done recently or where paint has been allowed to fall into disrepair. In these situations, paint tends to peel, chip, or flake. Young children are prone to swallowing these small pieces of paint. Even if the paint is not flaking or peeling, small children will chew on window sills and other painted surfaces when teething and ingest paint chips in the process.

If you suspect that your child has been exposed to lead paint or airborne lead, a blood test should be done to obtain an accurate lead level. Recent studies have indicated that severe, irreversible neurological damage may occur at lower levels than previously believed. It must be emphasized that medical science has only been able to develop treatments that may stop the progression of lead poisoning. Treatment does not prevent or reverse the signs and symptoms of lead-induced neurotoxicity. To be sure, lead poisoning in children causes devastating and permanent neurological damages. Thus, the best solution to the problem is total lead abatement in any living quarters where young children are expected to take up residence.

AGENT ORANGE EXPOSURE

In April of 2001 a committee of the National Academy of Science’s Institute of Medicine discovered that children of veterans of the Vietnam War may have an increased risk of a form of leukemia due to their fathers’ exposure to Agent Orange, a powerful herbicide used as a defoliant during the war. The chemical may cause acute myelogenous leukemia, or AML, in children. Of the several studies that were conducted, one found that childhood development of AML was more likely in the offspring of men who use pesticides and herbicides in their work. The report also confirmed that herbicide exposure may also be responsible for the development of soft-tissue cancer, Hodgkin’s disease, non-Hodgkin’s lymphoma and chloracne in veterans. Additional studies, however, are needed in order to prove that there is a link between Agent Orange and birth defects.

TANNING SALONS

A study which appeared in the April 2001 issue of the Journal of the American Academy of Dermatology showed that the UV exposure received from a tanning bed may be just as harmful to the skin as outdoor sun exposure therefore creating the same risk of developing skin cancer. More than one million (1,000,000) people in the Unites States visit tanning salons in an average day despite knowing that there is an increased incidence of melanoma in those who visit indoor tanning salons. Salon bulbs actually provide enough UVB and UVA radiation and both types of ultraviolet light, whether from the sun or tanning light, cause many types of skin damage that can lead to skin cancer. Salon-goers should view the tanning salon as the equivalent to spending the same amount of time at the beach on a sunny day.

EXHAUST FUMES

Environmentalists are concerned that children who ride to school on diesel-powered buses may be exposed to as much as four times more toxic exhaust than those who travel to school in passenger cars. It is estimated that these children might have an increased risk for developing cancer. While most modern buses are equipped with engines which emit less exhaust, keeping windows open in the bus or seating children closer to the front of the bus could minimize the potential risk.

PESTICIDES and DETERGENTS

New findings have indicated that women exposed to high levels of the pesticide DDT are more likely to have a premature baby or a baby that is considered small for its gestational age. DDT use can also increase infant mortality. Pregnant women should avoid prolonged or consistent exposure to DDT at all times.

In addition, pesticides present a serious problem in areas when the runoff from rain or flooding causes the residue to contaminate sources of drinking water (aquifers, reservoirs, and wells) or habitats used by edible fish and shell fish. Detergents from laundries (home and commercial), car washes, building cleanings, and other sources which are disposed of in public sewer systems also add to the contamination of our water supply. Certain studies also suggest that the stronger detergents (pH of 11 or more) may also present a risk of dermatitis, asthma, and conjunctivitis to those coming in direct contact with them or with clothing that has been laundered in them.

THE INDUSTRIAL SOLVENT 1,4-BUTANEDIOL

1,4-Butanediol is an industrial solvent, which along with another industrial solvent known as (gamma)-hydroxybutyrate, have been found to be extremely dangerous when ingested. Unfortunately, the fact that these solvents are converted to gamma-hydroxybutyrate, a drug of abuse with depressant effects on the central nervous system, has caused people to intentionally ingest the compounds in the form of a dietary supplement. The effects of these compounds, when ingested, can be quite severe. They include vomiting, urinary and fecal incontinence, agitation, combativeness, respiratory depression, decreased consciousness, and death. The compounds can be addictive. There is simply no reason to ingest these solvents in any form.

POWER PLANT EMISSIONS

Aging or poorly maintained coal-burning power plants are responsible for the emission of nitrogen oxides and sulfur dioxides which, in turn, cause significant levels of air pollution and acid rain. On August 7th, a federal judge in Ohio ruled that a utility company in that state had violated the Clean Air Act when it failed to install better pollution control devices in its coal-burning power plant. The case was brought by the Environmental Protection Agency along with the states of New York, New Jersey, and Connecticut which suffer from the effects of the air pollution caused by the toxic emissions from power plants in the Ohio Valley. Other cases brought against a number of other power companies operating over 48 plants have been settled.




www.hcop.org

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