Donen married and divorced five times and had three children. His first wife was dancer, choreographer and actress Jeanne Coyne. They married on April 14, 1948 and divorced in May 1951. Donen's second wife was actress Marion Marshall, who had been the girlfriend and protégé of Howard Hawks and later married actor Robert Wagner. Donen and Marshall had two sons together: Peter Donen, born in 1953, and Joshua Donen, born in 1955. They provided the name of Cary Grant's character in Charade. Donen and Marshall were married from 1952 until 1959. They had a lengthy custody battle over their two sons after Marshall married Wagner and Donen moved to England. Donen's third wife was Adelle, Countess Beatty. She had previously been the second wife of the 2nd Earl Beatty. They married in 1960, had one son (Mark Donen, born 1962), and lived together in London. They separated in 1969 before divorcing in 1971. Donen's fourth wife was American actress Yvette Mimieux. They were married from 1972 until 1985, but remained close friends after their divorce. Donen's fifth wife was Pamela Braden, thirty-six years his junior. Donen proposed to her four days after having met her. They were married from 1990 until 1994.
In the early 1940s Donen dated actress Judy Holliday while working on Broadway. He also dated Elizabeth Taylor for a year between his first and second marriages. Donen's current longtime companion is writer and director Elaine May, who he has dated since 1999 and claimed to have proposed marriage to "about 172 times.
Donen's eldest son Peter Donen was a visual effects artist who worked on such films as Superman III, Spaceballs, The Bourne Identity, and The Truth About Charlie. He also designed the title credits for Blame It on Rio. He died of a heart attack in 2003 at age 50. Donen's second son Joshua Donen is a film producer who worked on such films as The Quick and the Dead and Gone Girl, and the television series Spartacus: Blood and Sand. Mark Donen, Stanley's third son, worked as a production assistant on Blame It on Rio.
In 1959, Donen's father, Mordecai, died at 59 in Beaufort, South Carolina. His mother, Helen, died in 1989 at 84 in South Carolina, and Donen delivered the eulogy at her funeral.
With the deaths in the 2000s of Billy Wilder, George Sidney, Elia Kazan, Robert Wise, and Jules Dassin, Donen became the last surviving notable film director of Hollywood's Golden Age. He occasionally appears at film festivals and retrospectives and has continued to develop ideas for film projects. He was the subject of the 2010 documentary Stanley Donen: You Just Do It.
In December 2013 it was announced that Donen was in pre-production for a new film co-written with Elaine May, to be produced by Mike Nichols. A table reading of the script for potential investors included such actors as Christopher Walken, Charles Grodin, Ron Rifkin and Jeannie Berlin. In celebration of Donen's 90th birthday in 2014, a retrospective of his work titled "A Lotta Talent and a Little Luck: A Celebration of Stanley Donen" was held from July to August in Columbia, South Carolina. This retrospective included a tour of Donen's childhood neighborhood, a lecture by Steven Silverman and film screenings at the Nickelodeon movie theater, which Donen frequented as a child.