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Date Posted: 09:07:34 07/27/06 Thu
Author: Steve in ATL
Author Host/IP: dragonfire8.delta.com / 205.174.22.28
Subject: Not that I can see in the above. I cannot find the whle paper.
In reply to: sundaymorning 's message, "does it give a time frame?" on 08:49:13 07/27/06 Thu

>>The Effect of Alcohol Consumption on the Urinary
>>Testosterone / Epitestosterone Ratio
>>
>>
>>By Dr Simon Davis B.Sc., Ph.D.
>>
>>
>>Summary
>>
>>
>>Intoxicating beverages contain a number of different
>>forms of alcohol, the major constituent of which is
>>ethanol. When a beverage is consumed the ethanol
>>content passes through the stomach wall and digestive
>>tract into the blood stream. Once the ethanol enters
>>circulation it begins to alter the bodies'
>>biochemistry. One such reaction is to differentially
>>increase the rates of testosterone (T) and
>>epitestosterone (E) metabolism. The overall effect of
>>this reaction is to increase the ratio of T to E
>>excreted in the urine.
>>
>>
>>It has been reported that ethanol consumption can
>>increase urinary T/E ratios by 30% - 277% in healthy
>>individuals. Observed changes in plasma T/E ratios
>>can occur with the consumption of less than 2 pints of
>>lager. The ingestion of ethanol by an individual will
>>increase the T/E ratio observed in a urine sample.
>>
>>
>>It follows that if the effect of ethanol on T/E ratios
>>is calculated relative to urinary E concentrations, it
>>can be seen that increases in the ratio are
>>exponential as E concentrations decrease. Individuals
>>with naturally low E concentrations could, therefore,
>>experience increases in T/E ratios of ? 940% greater
>>than increases experienced in an individual with
>>normal E concentrations. Calculations estimate that
>>in individuals with low urinary E concentration,
>>ratios of 17 to 1 or higher could have resulted from
>>ethanol consumption without any administration of
>>exogenous T.
>>
>>
>>The current T/E ratio test as performed by Kings
>>College Laboratory and approved by the UK Sports, the
>>IWF and IOC cannot discriminate between a 13 to 1 T/E
>>ratio resulting from ethanol ingestion or a 13 to 1
>>ratio resulting from endogenous T administration.

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