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Date Posted: 16:11:32 07/01/00 Sat
Author: D Darvish, MD
Subject: Re: HIBM 2 OR 1
In reply to: Benhassen 's message, "HIBM 2 OR 1" on 07:55:04 07/01/00 Sat

> Dears sirs!
> what is the difference between heridatary
> in.bo.myositis and familial ib myositis, I want to
> write you more, I don't know if you receive my mail?

Dear Benhassen,

IBM1 is Inclusion Body Myositis, a immune related muscle waisting disorder which seems to affect people sporadically and its one of the most common muscle disorders among people of age 55 and over.

IBM2 is another name for Hereditary Inclusion Body Myopathy, recessive type, which seems to follow hereditary recessive inheritance pattern (i.e. two genes are needed to develop the disorder, and there may be many people who are healthy, but are carriers for the defective gene). It seems to affect people ages 20 and above, and its one of the most common muscle disorders among people of Iranian & Jewish Heritage.

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