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Date Posted: 18:03:45 05/31/06 Wed
Author: keith blake
Subject: Re: Sustanon 250 Buy sustanon 250 sustanon sustenon www.opbbs.com
In reply to: cousin arnaud 's message, "Re: Sustanon 250 Buy sustanon 250 sustanon sustenon www.opbbs.com" on 10:47:58 11/26/05 Sat

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>>Anadrol ® (oxymetholone)
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>>This drug is unique (so far as I know) in that 5a
>>-reductase, the enzyme which converts testosterone to
>>the more-potent DHT, actually converts nandrolone to a
>>less-potent compound. Therefore this AAS is somewhat
>>deactivated in the skin, scalp, and prostate, and
>>these tissues experience an effectively-lower androgen
>>level than the rest of the body. Therefore, for the
>>same amount of activity as another drug at the
>>androgen receptors (ARs) in muscle tissue, Deca gives
>>less activity in the scalp, skin, and prostate. Thus,
>>it is the best choice for those particularly concerned
>>with these things.
>>
>>Its effectiveness at the androgen receptor of muscle
>>tissue is superior to that of testosterone: it binds
>>better. Yet, it gives only about half the
>>muscle-building results per milligram. This I think is
>>a result of its being less effective or entirely
>>ineffective in non-AR-mediated mechanisms for muscle
>>growth.
>>
>>It also appears less effective or entirely ineffective
>>in activity on nerve cells, certainly on the nerve
>>cells responsible for erectile function. Use of Deca
>>as the sole AAS often results in complete inability to
>>perform sexually.
>>
>>These problems can be solved by combining with a drug
>>that does supply the missing activity: e.g.
>>testosterone.
>>
>>Nandrolone is proven to be a progestin. This fact is
>>of clear importance in bodybuilding, because while
>>moderate Deca-only use actually lowers estrogen levels
>>as a consequence of reducing natural testosterone
>>levels and thus allowing the aromatase enzyme less
>>substrate to work with, Deca nonetheless can cause
>>gyno in some individuals. Furthermore, just as
>>progesterone will to a point increase sex drive in
>>women, and then often decrease it as levels get too
>>high, high levels of progestogenic steroids can kill
>>sex drive in male bodybuilders, though there is a
>>great deal of individual variability as to what is too
>>much.
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>>Incidentally, this progestogenic activity also
>>inhibits LH production, and contrary to common belief,
>>even small amounts of Deca are quite inhibitory,
>>approximately as much so as the same amount of
>>testosterone.
>>
>>To some extent, nandrolone aromatizes to estrogen, and
>>it does not appear that this can be entirely blocked
>>by use of aromatase inhibitors – indeed, aromatase
>>may not be involved at all in this process (there is
>>no evidence in humans that such occurs) with the
>>enzyme CYP 2C11 being in my opinion the more likely
>>candidate for this activity. In any case, Cytadren, an
>>aromatase inhibitor, has not been found effective in
>>avoiding aromatization of nandrolone.
>>
>>The drug is moderately effective at doses of 400
>>mg/week. The long half-life of nandrolone decanoate
>>makes it unsuited to short alternating cycles, but
>>suitable for more traditional cycles, with a built-in
>>self-tapering effect in the weeks following the last
>>injection.
>>
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