Author: The O'Connells [Edit]
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Date Posted: 09:35:47 11/07/08 Fri
Here is a letter from Steve as an update of where he stands now and what we can be praying for! Please keep not only Steve in your prayers, but the medical staff that is assisting them in this decision and his girls, Joni, Faith, and Grace!
Deuteronomy 20:4 "For the LORD your God is the one who goes with you to fight for you against your enemies to give you victory."
Pray for victory for Steve!
Hi friends,
I just got back from 7 hours at the National Institutes of Health (NIH) AKA National Cancer Institute. First off, if this is any representation of how a government controlled medical facilities runs then I am 100% for it. I have never been to a more efficient and pleasant medical facility in my life. I have been to very nice hotels that did not offer the service that this place did.
I will try to condense 7 hours of meetings into a a paragraph or two. I will not know the next step until sometime next week but here is what I did learn. I will either get admitted to the study right now or I will have to try one more treatment before moving on to the NIH. The normal protocol is to start with a treatment called IL2 or Interleukin 2. It is a very toxic immunity booster that is 10X as potent as normal chemo. The procedure would be done at a major medical center like UCLA or the Mayo Clinic in Jacksonville, FL. It would be a week in the Hospital ICU then a week at home then a week back in ICU, followed by a month at home. This routine would then be repeated over if successful. This is a very accepted protocol but only works 5 to 8% of the time. If this is the route they want me to go then the procedures could start within the next week or so. The procedure has a very low success rate but when it does work it is a home run as close to a cure as there is for cancer.
Option 2 would be done at the NIH and is a process called Till, (T-cell immune ____ ____?) this is the removal of cancer tumors, the cells are separated and the healthy cells fighting the cancer are removed and then grown from a few thousand to several billion over 6-8 weeks. They take about 1cm of material and turn it into about 50 gallons of treatment that will be injected back into me. They use the same IL2 in option one to grow these cells and boost my immune system. If they decide to go with this option, I will go back in the next week or so to have a few tumors removed, I will then go back in about 6-8 weeks for three weeks of intense treatment. The first week I will get chemo every day in order to totally suppress my immune system and kill 100% of my white blood cells. Over the next 2 weeks I will get injected three times a day with the new "Super Charged" t-cells combined with the IL2. I will then go home and know in about 30 days if it works. Here are the odds on this treatment - There is a 50 to 60% chance that the tumors they remove will contain enough of the good t-cells to proceed further. The odds of this procedure shrinking the tumors at least 30% (how they define success) is about 50%. A couple of other figures - about one percent of the patients that under go this procedure develop severe side affects that normally result in death. If they cannot get enough tumors near the surface then they will have to cut them out from under and intertwined with my peck muscles. Because this area carries all of the blood vessels to my left arm, This means I will most likely lose some motion and control of the arm and worst case, the arm would have be removed down the road.
So once again we wait for the NIH to recommend the next course of action. The bottom-line is I am not sure which is the best way to go, we leave this problem up to God, he will make it clear what is the best for us. If it is option 1, we pray that I am one of the 5%, after all Joni thinks I am one in a million, or was that one in a hundred? If it is option 2, we first pray that they can easily harvest enough cells so that they do not have to go into my muscle, Next that I am not in the 1% that does not make it. (this point is rather important) Next that the three week process goes smoothly and I recover fast.. Lastly that I am in the 50% that have at least 30% shrinkage in my tumors, I am voting for 100% shrinkage, so I can be around another 44 years to keep my wife inline. Either way I feel great because God has a plan. A great plan for my life.
God Bless,
Steve
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