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Date Posted: 16:18:54 08/01/02 Thu
Author: Mondo
Author Host/IP: 199.214.48.10
Subject: Long Term Effects
In reply to: Sola 's message, "WOGGIE Admitted "Speed" Freak -THIS Explains His Lost Brain Function From A MEDICAL FACT!" on 14:27:40 08/01/02 Thu

Hi Sola,

Well, the long term effects aren't known yet. However, there is no doubt it is a very dangerous substance.




http://www.bnl.gov/bnlweb/pubaf/pr/2001/bnlpr030101.htm

Long-Term Effects
"We cannot reach any definite conclusions about long-term effects, because only three of the subjects had been detoxified for an extended period. But our three primary findings -- dopamine transporter loss, whole brain inflammation, and loss of motor and cognitive abilities -- document the adverse effects of methamphetamine to the human brain. We believe more studies must be done to assess if there is long-term damage from this drug," says Volkow. "We can say unequivocally that methamphetamine abusers need to be watched by their physicians as they age to determine whether they begin seeing any effects of neurodegenerative diseases like Parkinson's." The reduction in brain dopamine that occurs as these subjects age, in addition to the loss they experience from use of methamphetamine, may result in symptoms similar to those seen in Parkinson's disease, a severe movement disorder that results from a loss of dopamine in the brain.

Methamphetamine is a highly addictive stimulant that dramatically affects the central nervous system. Long reported as a dominant drug problem in southern California, methamphetamine abuse has recently become a substantial problem in other areas of the West and Southwest as well. Usage has also recently increased in areas of the Midwest and South. According to a survey by the National Institute on Drug Abuse, an estimated 4.9 million Americans have tried methamphetamine at some point in their lives.

Brookhaven scientists have done extensive research on addiction. Studies by Dr. Volkow and colleagues have shown that dopamine plays an important role in addiction to cocaine, nicotine, alcohol, heroin, and other drugs. Previous research at Brookhaven has shown that addictive drugs increase the level of dopamine in the brain while the subject is intoxicated, and that addicts have fewer dopamine receptors than non-addicts.

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