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Saturday, October 18, 04:52:03pm EDTLogin ] [ Main index ] [ Post a new message ] [ Search | Check update time | Archives: 1[2] ]


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Date Posted: 17:21:36 10/06/01 Sat
Author: Ani Bealaura
Subject: Rods barcode reactions

Hi Don and All,

Think about what this technology could be used for.

Rods barcode reactions
http://www.nature.com/nsu/011011/011011-2.html

"Using just two metals on a rod 6.5 micrometres long with bands of half a micrometre each, there are 4,160 possible combinations. With three metals, the number leaps to about 800,000. This is many more than the total number of genes in human cells, and so a different bar code could easily be assigned to every protein encoded by our genes."

"As the rods are much larger than most molecules, using them as tags is a bit like sticking a price label on a grain of salt. That doesn't matter as long as adding the label does not significantly alter the molecule's behaviour. For example, chain-like molecules that bind to gold might be used as flexible linkers that grasp the 'test molecule' at one end and a gold band on the rod at the other."

Kind Regards,

Ani

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