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Date Posted: 22:35:52 01/13/03 Mon
Author: m
Subject: Re: LIDOCAIN
In reply to: Reality Inc 's message, "Re: LIDOCAIN" on 01:06:13 01/12/03 Sun

Aus dem Klinikleitfaden Anästhesie :

Lidocain, Handelsname z.B. Xylocain, Wirkmechanismus : Antiarrhythmikum der Klasse 1B, Verminderung des schnellen Aktionspotentials, der Depolarisationsgeschwindigkeit, der Erregungsleitung, der Aktionspotentialdauer, der effektiven Refraktärzeit und der Kontraktionskraft, Verlängerung der Gesamtrefraktärzeit. Indikation : ventrikuläre Extrasystolen, Kammertachycardien. Alles in allem läuft die Wirkung auf eine Senkung der Herzfrequenz hinaus, das Lehrbuch für Pharmakologie und Toxikologie schreibt :"Bei zu hoher Dosierung.... kann auch ein Herzstillstand eintreten"

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