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Date Posted: 19:29:10 03/07/04 Sun
Author: David I.
Subject: Selecting against polygenic traits
In reply to: A Laura 's message, "DNA" on 08:06:48 03/06/04 Sat

Selecting against polygenic traits is tough. Much easier said than done. (see below)
_________________
"The most important factor in selecting against a polygenic disorder like hip dysplasia is to seek breadth of pedigree. Most breeders select normal parents with normal grandparents, and expect to produce all normal offspring. This is selection based on depth of pedigree. With polygenic traits, the hip status of breeding dogs’ siblings better represents the range of genes that can be present. With breadth of normalcy in the littermates of breeding dogs, and even of parents of breeding dogs, you are more efficiently selecting for a preponderance of those “normal-hip” genes."

Dr. Jerold S. Bell
Full Article
http://www.ashgi.org/articles/bone_joint_hip_dys.htm

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