| Subject: Shocking Event - End of human HIV trials 'a major blow' |
Author: Anul1
| [ Next Thread |
Previous Thread |
Next Message |
Previous Message
]
Date Posted: Thu, Nov 08 2007, 08:29:11pm
In reply to:
TapuMalo
's message, "Shocking Event" on Wed, Nov 07 2007, 09:55:04am
End of human HIV trials 'a major blow'
November 8, 2007 - 6:20PM
Source: ABC
A researcher says the end of the trials is a major blow (File Photo).
Photo: AAP
A leading Australian vaccine researcher says the end of human trials of a promising HIV vaccine is a major blow to hopes that any vaccine will halt the spread of AIDS.
The Merck company today released an analysis of cancelled trials which suggest that its vaccine might have increased susceptibility to HIV infection.
Nine Australians are believed to be among thousands of people who are unaware a once-promising vaccine for AIDS has increased their infection risk after they participated in clinical trials around the world.
Professor Ian Ramshaw from the John Curtin School of Medical Research says it is highly significant news after disappointing results from a number of other HIV vaccine trials.
"This is one of the larger trials where they're basically looking at susceptibility and it's extremely disappointing, because the immunity is quite high in these individuals," he said.
"It means, by the looks of things, there won't be a HIV vaccine for a good while yet, whether we'll get one at all."
Trials cancelled
The multinational trials involving more than 3,000 HIV-negative volunteers were cancelled in September after a large-scale study found the vaccine was not effective at preventing infection.
Researchers have this morning revealed far worse news - those who received the V520 vaccine are more susceptible to acquiring the AIDS virus.
The volunteers were warned to protect themselves from exposure to AIDS but were not told if they were administered the vaccine or the inactive placebo.
The information was kept secret to minimise biases in the study.
Scientists will decide over the next 10 days whether those involved in the trial should be told about whether they were given the vaccine or not.
Merck says volunteers can opt out of the study now and be told if they were given the HIV vaccine.
All but one of the infections were in male volunteers and the bulk of those infected were homosexual men.
[
Next Thread |
Previous Thread |
Next Message |
Previous Message
] |
|